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presentation-notes

Presentations seen and transcribed by David Eccles

GridION X5 - The Sequel

A presentation by Clive Brown, CTO Oxford Nanopore Technologies; notes by David Eccles, 2017-Mar-15. See the presentation here.

Image of Clive Brown holding a GridION

Preface

How nanopore sequencing works

decoding signals

MinION device

Technology workflow

PromethION; elephant in the room

On-demand sequencing on PromethION

PromethION Flow cell performance

PromethION scaling

PromethION performance and yield

Instrument shipping

PromethION Flow cells

PromethION design change

What’s inside the compute box

PromethION evolution

Base call acceleration

Base call acceleration design

Base call benchmarking

PromethION base call implementation

MinION compute requirements

Accuracy / chemistry / algorithm

Consensus accuracy

Homopolymers

Novel base calling

Homopolymer

Base calling from raw signal

Base caller landscape

Other accessory tools

Throughput

Software improvements to throughput

Read length

Upcoming improvements for throughput and sensitivity

Improving / replacing 2D

1D^2

1D^2 consensus

Traces

1D^2 accuracy

1D^2 release

New product; MinION well established

Offerings

GridION

What is GridION

GridION X5

GridION Production

GridION Pricing

Also Nanopore service certified

Summary tables for 3 products

Shop opens for GridION next week

Dates

Lots of things Clive hasn’t spoken about

Questions